| Date | Opponent | Location | TV | Outcome/Time |
| 11/19/2004 | Iowa (KCRG-TV 9 Hawkeye Challenge) | Iowa City, Iowa | L, 66-50 Recap | Final Stats | |
| 11/20/2004 | vs. Northern Illinois (KCRG-TV 9 Hawkeye Challenge) | Iowa City, Iowa | L, 61-43 Recap | Final Stats | |
| 11/22/2004 | Wisconsin | Madison, Wis. | L, 82-53 Recap | Final Stats | |
| 11/28/2004 | Tennessee Tech | Carbondale, Ill. | L, 73-55 Recap | Final Stats | Photo Gallery | Gametracker | |
| 12/01/2004 | SE Missouri State | Carbondale, Ill. | L, 77-56 Recap | Box Score | Gametracker | |
| 12/07/2004 | Saint Louis | Carbondale, Ill. | W, 69-53 Recap | Final Stats | Gametracker | |
| 12/11/2004 | Southern Mississippi | Hattiesburg, Miss. | L, 55-48 Recap | Final Stats | |
| 12/18/2004 | Bethune Cookman | Daytona Beach, Fla. | W, 69-64 Recap | Final Stats | |
| 12/21/2004 | Stetson | Deland, Fla. | L, 63-55 Recap | Final Stats | |
| 12/31/2004 | Creighton* | Carbondale, Ill. | L, 85-63 Recap | Final Stats | Gametracker | |
| 01/02/2005 | Drake* | Carbondale, Ill. | L, 70-49 Recap | Final Stats | Gametracker | |
| 01/06/2005 | Wichita State* | Wichita, Kan. | L, 67-52 Recap | Final Stats | |
| 01/08/2005 | Southwest Missouri State* | Springfield, Mo. | L, 78-48 Recap | Final Stats | |
| 01/14/2005 | Northern Iowa* | Carbondale, Ill. | L, 64-40 Recap | Final Stats | Gametracker | |
| 01/16/2005 | Bradley* | Carbondale, Ill. | L, 68-42 Recap | Final Stats | |
| 01/22/2005 | Evansville* | Carbondale, Ill. | L, 54-53 Recap | Final Stats | Gametracker | |
| 01/27/2005 | Indiana State* | Terre Haute, Ind. | L, 78-66 Recap | Final Stats | |
| 01/29/2005 | Illinois State* | Normal, Ill. | L, 81-44 Recap | Final Stats | Gametracker | |
| 02/03/2005 | Wichita State* | Carbondale, Ill. | W, 69-42 Recap | Final Stats | |
| 02/05/2005 | Southwest Missouri State* | Carbondale, Ill. | L, 88-62 Recap | Final Stats | Gametracker | |
| 02/10/2005 | Northern Iowa* | Cedar Falls, Iowa | L, 72-43 Recap | Final Stats | Gametracker | |
| 02/12/2005 | Bradley* | Peoria, Ill. | L, 70-60 Recap | Final Stats | |
| 02/19/2005 | Evansville* | Evansville, Ind. | L, 67-55 Recap | Final Stats | |
| 02/25/2005 | Indiana State* | Carbondale, Ill. | L, 94-51 Recap | Final Stats | Gametracker | |
| 02/27/2005 | Illinois State* | Carbondale, Ill. | L, 66-59 Recap | Final Stats | Gametracker | |
| 03/03/2005 | Creighton* | Omaha, Neb. | L, 78-58 Recap | Final Stats | |
| 03/05/2005 | Drake* | Des Moines, Iowa | L, 75-53 Recap | Final Stats |
