Following this weekend, the Salukis only play two more matches at Davies Gym this season.
SIU was led by sophomore Meg Viggars, with 10 kills for a .444 hitting efficiency.
Southern opens with Florida Gulf Coast (9 a.m.) and Auburn (4:30 p.m.) on Friday.
Southern is looking to avenge a five-set loss to the Blue Raiders at home in 2013.
Junior Taylor Pippen (8 kills, 16 attacks, .375), freshman Andrea Estrada (7 kills, 23 attacks, .174) and freshman Abby Barrow (7 kills, 17 attacks, .353) combined for 22 kills.
Head shots and team shots of the 2014 SIU Volleyball team.
Averaged 0.80 kills per set, 0.23 digs per set and 0.77 blocks per set Contributed six kills and four assists in SIU's match against Long Beach State Played in 16 matches and started five.