| Date | Location | Result | |
| 11-17-12 | Carbondale, Ill. | Southern Illinois 35, Western Ill. 0 | Box score |
| 11-03-12 | Carbondale, Ill. | South Dakota St. 16, Southern Illinois 12 | Box score |
| 10-27-12 | Fargo, ND | North Dakota State 23, Southern Illinois 17 | Box score |
| 10-20-12 | Youngstown, Ohio | Southern Illinois 38, Youngstown State 21 | Box score |
| 10-13-12 | Carbondale, Ill. | Southern Illinois 34, Northern Iowa 31 | Box score |
| 10-06-12 | Normal, Ill. | Southern Illinois 17, Illinois State 0 | Box score |
| 09-29-12 | Carbondale, Ill. | Indiana State 24, Southern Illinois 3 | Box score |
| 09-22-12 | Springfield, Mo. | Southern Illinois 14, Missouri State 6 | Box score |
| 09-15-12 | Carbondale, Ill. | Southern Illinois 35, SE Missouri St. 14 | Box score |
| 09-08-12 | Oxford, Ohio | Miami 30, Southern Illinois 14 | Box score |
| 08-30-12 | Charleston, Ill. | Eastern Illinois 49, Southern Illinois 28 | Box score |
